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In contrast, the vast majority of listed option buyers never exercise; they simply sell their options on the open market Many of these people are speculators who only expect to hold their option for a short time Once the underlying makes a move in the expected direction (or perhaps a move in the wrong direction), they sell In a sense, up to expiration day, options are like hot potatoes being tossed around among the market of speculators Such activity accounts for quite a bit of the options trading volume but not all of it Another major source of trading volume is institutional investors They may use options to hedge large positions, or simply trade large positions for speculation Until now we have only talked about options to buy Options to buy something at a stated price for a limited time are call options.

indeed, for mapping genes via linkage, sets of markers are chosen because of their high heterozygosity or other similar measures of their information content (Botstein et al., 1980). Although genetic considerations lead to unbalanced numbers in each group, statistical considerations are often most advantageous with balanced numbers. Judicious statistical design is of paramount importance for controlling costs while maintaining adequate statistical power to test hypotheses. This is of particular concern in the context of clinical trials that require extensive study of individuals in the trial. By establishing a two-stage sampling for studies, both considerations can be reconciled. For example, an initial screen of individuals for a clinical trial may involve minimal examinations of a large number of potential participants followed by genotyping. Once candidates are genotyped, a balanced subset representing the genotypic groups can be selected for the full intervention. Statistical power is maintained (likely enhanced) while minimizing the required sample sizes. Such designs will be required to test the ef cacy of treatments by genotype.

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UMTS uses channels on the air interface as shown in the previous section. As on any interface, several protocol layers are used for encapsulating the data and sending it to the correct recipient. In UMTS Release 99 the RNC is responsible for all protocol layers except for the physical layer which is handled in the Node-B. The only exception to this rule is the BCCH, which is under the control of the Node-B. This is because the BCCH only broadcasts static information that does not have to be repeatedly sent from the RNC to the Node-B. As is shown in Figure 3.19, higher layer PDUs (packet data units) are delivered to the RNC from the core network. This can be user data like IP packets or voice frames, as well as control plane messages of the MM, CM, PMM, or SM subsystems. If the PDUs contain IP user data frames, the PDCP (packet data convergence protocol) can optionally compress the IP header. The compression algorithm used by UMTS is described

But there is another type of option an option to sell something While these options can be a bit more difficult to conceptualize, options to sell something at a stated price for a limited time are known as put options..

COPS [Durham et al, 2000] was the rst policy-related protocol to be standardized by the IETF This section provides some background about the motivation for this work and the resulting standards that were developed 3111 Overview The service model of the Internet is based on packet switching; that is, data are inserted into packets, which are carried from the source to their destination based on information in the packet header The IP packet header contains information such as the source and destination IP addresses of the packet, the source and destination ports, and other relevant data that are used to route the packet to its destination In general, all packets are treated equally with respect to scheduling them for delivery; this paradigm came to be known as best effort delivery.

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The XSP must rent from the local telephone company both the local loop and collocation space for his equipment He must also buy transport services to connect his POP to the ISPs If the local telephone company is running its own XSP and/or ISP services, it has the incentive to create unfavourable market conditions for the competing XSP Although the regulator can control the rental price of the local loop, it is hard for him to control other subtle issues These include the price and true availability of collocation space, the timely delivery of local loop circuits, the maintenance of these circuits and the tracking of malfunctions These same issues also arise in other access technologies and show the intricacies of the underlying business models.

FIGURE 7.1 a Side view of a two-layer patch array fed by probes. b Modular representation of the array.

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