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collagenous and elastic ligaments permit a limited degree of exion, extension, rotation, and lateral motion of the spine The stability of the spine depends on the integrity of the vertebral bodies and intervertebral discs and on two types of supporting structures, ligamentous (passive) and muscular (active) Although the ligamentous structures are quite strong, neither they nor the vertebral body disc complexes have suf cient integral strength to resist the enormous forces that may act on the spinal column; the stability of the lower back is therefore largely dependent on the voluntary and re ex activity of the sacrospinalis, abdominal, gluteus maximus, and hamstring muscles The vertebral and paravertebral structures derive their innervation from the meningeal branches of the spinal nerves (also known as recurrent meningeal or sinuvertebral nerves) These meningeal branches spring from the posterior divisions of the spinal nerves just distal to the dorsal root ganglia, re-enter the spinal canal through the intervertebral foramina, and supply pain bers to the intraspinal ligaments, periosteum of bone, outer layers of the annulus brosus (which enclose the disc), and capsule of the articular facets Coppes and associates have found A- and C pain bers extending into the inner layers of the annulus and even the nucleus pulposus Although the spinal cord itself is insensitive, many of the conditions that affect it produce pain by involving these adjacent structures For example, the sensory bers from the lumbosacral and sacroiliac joints enter the spinal cord via the fth lumbar and rst sacral roots Motor bers exit through the corresponding anterior roots and form the efferent limb of segmental re exes The sympathetic nerves contribute only to the innervation of blood vessels The spinal roots in the lumbar region, after exiting from the spinal cord, course downward in the spinal canal and are gradually displaced laterally until they angulate and exit at the intervertebral foramina Prior to entering the short foraminal canal, the spinal root lies in a shallow furrow along the inner surface of the pedicle called the lateral recess This is a common site of root entrapment by disc fragments and bony overgrowth The parts of the back that possess the greatest freedom of movement and hence are most frequently subject to injury are the lumbar, lumbosacral, and cervical In addition to bending, twisting, and other voluntary movements, many actions of the spine are re exive in nature and are the basis of posture Aging Changes in Spinal Structures Changes in the intervertebral discs and ligaments as a consequence of aging and perhaps a succession of minor traumas begin to occur as early as the rst part of the third decade Deposition of collagen and elastin and alterations of glycosaminoglycans combine to decrease the water content of the nucleus pulposus; concomitantly, the cartilagenous end plate becomes less vascular (Hassler) The dehydrated disc thins out and becomes more fragile Similar changes occur in the annulus of the disc, which frays to an increasing degree with the passage of time, permitting the nucleus pulposus to bulge and, sometimes with injury, to extrude This process can be observed by magnetic resonance imaging (MRI), which shows a gradual re-. asp.net mvc display pdf Upload pdf files in ASP.net - CodeProject
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4 Sep 2017 ... If I want to display a PDF file in the browser instead of downloading a copy, I can tell the browser via an additional Content-Disposition ... duction in the high signal of the nucleus pulposus with the passage of time In women who had MRI for gynecologic reasons, Powell and coworkers found an increasing frequency of lumbar disc degeneration and bulging, approaching 70 percent by the ftieth year of life Similar abnormalities in asymptomatic men and women have been recorded by Jensen and colleagues The shrinkage of the disc alters the alignment of the articular facets and vertebral bodies, leading sometimes to facet arthropathy and bony spur formation The latter changes may contribute to stenosis of the spinal canal and also compromise the lateral recesses of the canal and the intervertebral foramina, where they impinge on nerve roots Osteoporosis, especially in older women, is an important cause of vertebral attening or collapse, additionally narrowing the spinal canal asp.net mvc pdf viewer control C# render pdf in browser using MVC - Tallcomponents
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